Based on China's current Covid policy (zero-Covid strategy), how to carry out nucleic acid test for all residents in extremely fast and low cost way is very critical. The task is massive and incredible. But we make it combined Mastars' tooling / injection molding capabilities/capacities, automation technology and medical experience. Now the test cost is less than US$0.1 per person each time. China's manufacturing supply chain is reliable and durable always even during the pandemic.
The first Chinese anti-new crown oral drug pricing disclosed. The initial price of Azivudine tablets for the treatment of neointimal pneumonia was set at no more than 300 yuan per bottle, 35 tablets per bottle, 1 mg per tablet.
Real Biologics' Azivudine Tablets is an orally administered small molecule Neocoronavirus pneumonia treatment developed independently in China, and on July 25, the registration application for Azivudine Tablets to add an indication for the treatment of Neocoronavirus pneumonia was approved with conditions
Prior to that, Pfizer's neo-coronavirus treatment drug nematovir tablets/ritonavir tablets combination package (i.e. Paxlovid) was conditionally approved for marketing by the State Drug Administration in February 2022, making it the first imported anti-neo-coronavirus oral drug to be approved in China. In terms of technical route, Pfizer's oral small molecule neo-coronavirus treatment Paxlovid is a 3CL protease inhibitor and Azulfidine tablets belong to the nucleoside class of drugs (RdRp inhibitors).
In terms of price, the pricing of the first Chinese oral anti-neoconazole drug is 1/10 of that of imported oral anti-neoconazole drugs. based on a price of less than 300 yuan per bottle, Azivudine tablets are priced at about 8.5 yuan per tablet. Public information shows that Paxlovid has been distributed to at least 8 provinces and municipalities directly under the Central Government, including Jilin, at a price of RMB 2,300 per box. Each box of Paxlovid contains 20 tablets of nematovir and 10 tablets of ritonavir. Based on this calculation, Paxlovid is priced at approximately RMB 76 per tablet.
In terms of indication, Azulfidine tablets are used to treat adult patients with common COVID-19. Paxlovid is used to treat adults with mild to moderate novel coronavirus pneumonia (COVID-19) with risk factors for progression to severe disease, such as patients with high risk factors for severe disease such as advanced age, chronic kidney disease, diabetes, cardiovascular disease, and chronic lung disease.
In terms of regimen, the dosage of Paxlovid is 300 mg of nematovir tablets (neo-coronavirus protease inhibitor) taken concurrently with 100 mg of ritonavir tablets (antiviral booster) every 12 hours for 5 days, and one box is sufficient to complete a course of treatment. The dosage of Azivudine tablets is 5 tablets a day for a course of 7 days, one bottle is the dosage of one course of treatment.
Real Biologics issued an article on August 2, saying that Azulfidine tablets officially entered into production. At present, the company's Pingdingshan production base annual production capacity is 1 billion tablets, the future may achieve an annual capacity of 3 billion tablets.
